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The World Health Organization (WHO) is equally wary, saying that until e-cigarettes have been endorsed as safe and effective by national regulators, consumers should be strongly advised not to use any of these products. Supporters of e-cigarettes scoff at suggestions they are a hazard or could be a slippery slope for previously addiction-free young people to get hooked on nicotine

Histone modification and pulmonary vascular endothelial cell apoptosis Histone modification refers to histone acetylation, ubiquitination, phosphorylation, or methylation