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First, psychoactive substances, especially nicotine, can impact circadian rhythms through behavioral entrainment, thereby altering an individuals optimum performance [25]

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Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu Tobacco Induced Diseases 9

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