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Smokers who used e-cigarettes within 5 years of quitting in this group had a 1.26 (95% CI, 1.03-1.54) times greater risk for lung cancer than those who did not use e-cigarettes within 5 years of quitting

Chromatin immunoprecipitation of FOXO1 and FOXO3a demonstrated increased binding of the former to promoter regions of autophagy genes- BECLIN1 , ATG5 , ATG12 , ATG16 , and LC3 in CSE challenged cells

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They found no evidence that those recruits were riskier across the board than any others

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Detectability of Electronic Cigarettes The answer is yes