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The skin will then have difficulty removing them easily, leading to a build-up of dead skin cells and the development of acne

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10.1183/13993003.00374-2016 Eur Respir J

This provokes inflammatory signaling cascades mediated by damage-associated molecular patterns (DAMPs), receptors like RAGE and TLRs, and downstream cytokines and kinases (Prez Ros et al

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