Pairing medication with the power of behavior change Weight-loss medications can produce exceptional results, but meds alone arent enough
Over the years, studies have shown them to be safe and effective when taken as prescribed
Because of its central role in metabolic regulation, the GLP-1 signaling axis has become a major therapeutic target for the treatment of obesity and type 2 diabetes
00:04:41 Vickie Danaher However, the approved and marketed products, so what were actually going to see in our pharmacies, is an orforglipron tablet with strengths ranging from 0.8 milligrams to 17.2 milligrams
The pace of titration can be slowed if side effects are problematic or if weight loss is satisfactory at a lower dose
Meta-analyses demonstrate that both GLP-1RAs and SGLT2i reduce the risk of major adverse cardiovascular events (MACE) to a comparable extent, while SGLT2i provide superior benefits in mitigating hospitalization for heart failure and slowing chronic kidney disease progression