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[26] [27] Some electronic cigarettes contain synthetic nicotine analogues (for example, 6-methyl nicotine, sometimes marketed under the trade name "Metatine") [28] and makers are trying develop nicotine substitutes

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Cigarette smoke is a complex aerosol made up of thousands of tiny chemical molecules, such as nicotine, tar, and volatile organic compounds

And there are properties of the THC in cannabis that may cause anxiety, which can make both your heart rate and blood pressure go up