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24 The GBD 2019 study ranked high systolic BP and tobacco use among the top global risk factors for death and DALYs

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Some argue that as long as a drug harms only those who choose to use it, the state should let individuals make their own decisions, limiting its role to ensuring that users are informed of the risks that they are running

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Anhedonia does, however, appear to be associated with aberrant brain activity

Hypertension, 37 (2), 187193