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We followed a guideline named PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) when writing the review article (14)

Smoking gun The term " smoking gun " is a reference to an object or fact that serves as conclusive evidence of a crime or similar act, just short of being caught in flagrante delicto

643828 Prokhorov AV, Hudmon KS, Stancic N (2003) Paediatr Drugs 5:110 Pryor WA, Stone K, Zang LY et al (1998) Chem Res Toxicol 11:441448 Richter E, Engl J, Friesenegger S et al (2009) Chem Res Toxicol 22:10081017 Rodgman A, Perfetti T (2009) The Chemical Components of Tobacco and Tobacco Smoke

The endocrine part produces insulin and other hormones

From January 2017 to March 2022 in the United States, the unit share of e-cigarettes containing 5% nicotine strength substantially surged to 1486.3%, whereas the dollar share notably increased to 1345.5% 11