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Nerve-specific extracellular matrix hydrogel promotes functional regeneration following nerve gap injury

Polymeros D, Beintaris I, Gaglia A, Karamanolis G, Papanikolaou IS, Dimitriadis G, Triantafyllou K

Validate key regulators (e.g., cell type-specific lncRNAs and lipid metabolic enzymes) using kidney organoid models, particularly patient-derived organoids (PDOs) that recapitulate disease-specific phenotypes (e.g., diabetic nephropathy and focal segmental glomerulosclerosis)

We will continue his protocol of TPE with 5% albumin replacement, UCT-MSC-EXs, Epitalon, and Semax indefinitely

In comparison, native GLP-1 is eliminated by both the kidneys and liver while also subject to metabolism in peripheral tissues