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Similar effects may occur within the stomach, as smokers have a significantly higher incidence of peptic ulcer disease, intestinal metaplasia, and dysplasia than nonsmokers 11, 12
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126 Interestingly, levels of the acrolein metabolite, 3HPMA, were found to be elevated in urine samples obtained from ecigarette smokers when compared with nonsmokers, confirming its systemic delivery to the human body