Differentially expressed genes upon miR-320d overexpression are involved in the IL-1/NF-B signaling Since we previously observed that miR-320d is able to reduce IL-1-induced activation of the pro-inflammatory factor NF-B [14], we specifically investigated expression of ERK, IKBKB, IRAK1-4, JNK, MAP3K7, MYD88, p38, TAB1, TAB2 and TRAF6, genes involved in this pathway [22]
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Crohns disease can occur in people of all races and ethnicities and is increasing all over the world