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Individuals with a high GRS were more than twice as likely to experience nausea from liraglutide, a widely used GLP-1 receptor agonist, compared to those with a low GRS (68% versus 30%)

Last Published 06.01.2026 Effective Date: 06.01.2026 This policy addresses the use of Oxlumo (Lumasiran) and Rivfloza (Nedosiran) for the treatment of primary hyperoxaluria type 1 (PH1)

Furthermore, the administration of denatonium benzoate, in conjunction with gavage of glucose, causes the secretion of GLP-1 and subsequently elevates plasma insulin levels and reduces plasma glucose in db/db mice [195]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Haddad F, Adams GR