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Effects of Excess/Deficiency of Other Pituitary Hormones on Glucose Homeostasis In contrast to the frequent and sometimes severe effects of hypercortisolism and GH excess, the deficiency or excess of other pituitary hormones have also been shown to affect glucose homeostasis but mostly to a less severe extent

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Retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors, distinguishing it from currently approved therapies such as semaglutide and tirzepatide