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10.1038/s42255-020-00327-x 50 GromadaJ.FranklinI.WollheimC

The bacteriostatic water used for reconstitution provides antimicrobial protection but does not prevent peptide bond hydrolysis at elevated temperatures

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Build these into your routine: Keep a current medication list and share it with your hearing care provider Ask your prescriber whether any of your drugs carry ear risk Report new symptoms quickly instead of waiting Protect your ears from loud noise, which adds to the risk Stay hydrated, watch your blood sugar, and go easy on smoking and alcohol These habits will not undo old damage

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Appears or worsens after a dose increase