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4 The results from ESSENCE confirmed a statistically significant improvement in the resolution of steatohepatitis (liver injury), with no worsening of liver fibrosis, as the first primary endpoint, and a reduction in liver fibrosis (liver scarring), with no worsening of steatohepatitis as the second primary endpoint compared to placebo
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Efficacy and Safety of Once-Weekly Semaglutide Versus Daily Canagliflozin as Add-on to Metformin in Patients with Type 2 Diabetes (SUSTAIN 8): A Double-Blind, Parallel-Group, Phase 3B Trial
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