It is a dual-agonist, meaning it mimics two natural gut hormones: GLP-1 (Glucagon-Like Peptide-1) and GIP (Gastric Inhibitory Polypeptide)
This leads to significant weight loss over time, especially when combined with a healthy diet and exercise
Wright DT, Cohn LA, Li H, Fischer B, Li CM, Adler KB: Interactions of oxygen radicals with airway epithelium
What is Tirzepatide
Melbourne bodybuilder Aaron Curtis says he does not use any drugs for weight loss, but he also told triple j Hack that at least three of his non-bodybuilding clients at his gym do
For instance, monoterpene nerol activates OR2W3, which triggers Ca 2+ influx and then co-activates TMEM16A and CFTR, ultimately leading to smooth muscle relaxation and bronchodilation (6)