[8] [9] GLP-1 medications work through several complementary mechanisms: Enhancing insulin secretion from pancreatic beta cells in response to elevated blood glucose Suppressing glucagon release , which reduces glucose production by the liver Slowing gastric emptying , helping you feel fuller for longer Acting on appetite centres in the brain to reduce hunger and food intake In the UK, commonly prescribed GLP-1 receptor agonists include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), lixisenatide (Lyxumia) and exenatide (Byetta, Bydureon)
Instead of escalating procedural complexity, we may be able to improve outcomes by targeting the biology of the disease itself. More from the Miller School of Medicine Learn how the safer, faster pulsed field ablation procedure restored one patients heart rhythm and quality of life
Rehfeld 2018
Understanding GLP-1 Weight Loss Medication Options How Do Oral GLP-1 Tablets Compare to Injections
Diabetes is an endocrine disorder, and the endocrine system coordinates a delicate hormonal interplay
doi: 10.1186/s12933-020-01148-8, 18 ChristensenS.RobinsonK.ThomasS.WilliamsD