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doi:10.1038/s41430-025-01636-8

The GLP-1 receptor belongs to the G protein-coupled receptor (GPCR) B family, consisting of seven transmembrane helices (TMH) interconnected by intracellular loops, with a C-terminal intracellular domain and a large (~120 amino acid) N-terminal extracellular domain (ECD) (65)

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This narrow margin leaves little room for error

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