209 Endogenous GLP-1 has also been suggested to promote beta-cell proliferation in rodent cell lines and isolated rodent islet cells in addition to inducing apoptotic resistance
doi: 10.1111/bcpt.12974 135 TeramotoSMiyamotoNYatomiKTanakaYOishiHAraiHet al
The pancreatic effects of GLP-1 receptor activation in humans appear to be complex and likely influenced by individual patient factors, pre-existing pancreatic health, and concurrent metabolic conditions
Moschovaki Filippidou F, Kirsch AH, Thelen M, Ktszeri M, Artinger K, Aringer I, et al
It becomes especially relevant for patients with pre-existing cardiovascular concerns
GLP-1 receptor agonists work by slowing gastric emptying, reducing appetite, and decreasing overall food intake