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Chem Res Toxicol 13:363372

Villanova, F., Di Meglio, P

then, we laparatomized the rat for portal vein, inferior vena cava, and abdominal aorta pressure recording

The goal of this design was to ensure that the cytotoxic payload remained conjugated to the antibody during systemic circulation, minimizing premature drug release and off-target toxicity 57

Despite the advantages and good treatment outcomes of using in-situ TYR-catalyzed DeTYR formation as a treatment modality in treating melanin, this strategy has certain weaknesses

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