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When this phenomenon was first discovered in the early 1920s, the hypothesis explaining this metabolic reprogramming from OXPHOS to glycolysis was mitochondrial dysfunction [2]

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Neutrophils play important roles in early anti-microbial responses destruction through the release of proteins such as neutrophil elastase and matrix metalloproteinases (MMPs) as well as reactive oxygen species (ROS)

1,3-dipalmitoylglycerol ester of chlorambucil as a lymphotropic, orally administrable anti-neoplastic agent