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Now, to understand the whole debate, we need to step back a little and start from the very basics, such as what glutathione is, what it does, and what happens when its levels are changed in the body

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Shen MY, Liu TI, Yu TW, Kv R, Chiang WH, Tsai YC et al (2019) Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer

2022;27:165e222

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For this reason, challenges in affinity purification are not only how to optimize methods to obtain highly pure proteins, but also in developing bioinformatic methods to differentiate true protein interactions from background interactions