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Despite the encouraging results of GLP-1/glucagon co-agonism in experimental models, different GLP-1 and glucagon co-agonists have shown various levels of efficacy and tolerability in people with obesity and/or T2D, in early phase clinical trials, which may be explained by the different ratio of GLP-1 to glucagon activity between the different molecules [65]

Its not just about diabetes treatment either, its about the impact of reducing the prognosis for those with obesity who have developed prediabetes and will, without intervention, develop Type 2 Diabetes

Characterization of attributes and in vitro performance of exenatide-loaded PLGA long-acting release microspheres