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Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

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In conclusion, GLPs hold substantial translational potential for managing diverse wound pathologiesincluding diabetic ulcers, thermal burns, and intestinal mucosal damageby orchestrating a coordinated, multi-modal therapeutic response: stimulating epithelial and stromal cell proliferation/migration

Furthermore, in the absence of tryptophan, neoantigens generated by the substitution of this amino acid for phenylalanine in proteins can be targeted by T cell-mediated immune responses [155]

[DOI] [PubMed] [Google Scholar] 17.Flagg EW, Coates RJ, Eley JW, Jones DP, Gunter EW, Byers TE et al